Acids secreted by stomach helps to kill harmful bacteria in gastrointestinal (GI) tract apart from digesting food. Long term use of antacid may decrease production of acid or increase the pH in GI tract. This situation can favor development of certain harmful bacteria in GI tract.These bacteria can spread other diseases and release endotoxin that can worsen ulcer. Therefore, do not use antacids for long time without consulting doctor.
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